You can control your smart heating from your Mac or from your PC. This is true whether you have selected a Nest smart thermostat solution or a Honeywell Evohome multi-zone heating solution.
Just log into your Nest or Honeywell accounts by going to their respective websites via a browser. However, control is not as intuitive as using an app on your phone or tablet.
You may also find third-party apps that work on desktops. We cannot advise on how well these work